The University of Missouri is a public land-grant research university in Columbia, Missouri, United States. It is Missouri's largest university and the flagship of the four-campus University of Missouri System. Founded in 1839, MU was the first public university west of the Mississippi River. It has been a member of the Association of American Universities sinc…The University of Missouri is a public land-grant research university in Columbia, Missouri, United States. It is Missouri's largest university and the flagship of the four-campus University of Missouri System. Founded in 1839, MU was the first public university west of the Mississippi River. It has been a member of the Association of American Universities since 1908 and is classified among "R1: Doctoral Universities – Very high research activity."