Cell-line development enhances biopharmaceutical production capacity and quality, but complex biologics like bsAbs and ADCs ...
Pharmaceutical Technology on MSN
AGC Biologics to expand cell line development with ATUM partnership
AGC Biologics is set to expand its Cell Line Development Centre of Excellence through a partnership with ATUM for integrating the Leap-In transposase expression platform into its services.
U.S. government researchers have made a significant step forward in developing a fully automated process for cell-line development. The National Institute of Allergy and Infectious Diseases (NIAID), ...
Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...
Host Cell Line Selection: The first critical step is selecting the appropriate host cell line. This decision is based on factors such as growth characteristics, genetic stability, and productivity, ...
To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide ...
Integrated analytical workflows are transforming cell line development by combining faster screening and streamlined decision-making.
Luciferase-based reporter cell lines are invaluable for detecting cellular responses to signaling pathways in vitro, enabling high-throughput screening and profiling of inhibitors or activators. In ...
Cell line development continues to face technical and operational hurdles in transfection, clone selection, and media optimization. Manual screening, extended culture timelines, and fragmented data ...
Successful commercialization of a biopharmaceutical product is dependent upon an effective, high-quality cell-line development process. While high-throughput analytical instruments often take center ...
New offering provides drug developers with flexible and powerful cell line development options for monoclonal antibodies, multi-specific and complex molecules SEATTLE--(BUSINESS WIRE)--As drug ...
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