Intel processors have always powered NUCs. However, things changed when Asus took over the NUC line from the chipmaker in 2023. The manufacturer is seemingly experimenting with AMD chips after customs filing discovered by ComputerBase (machine translated) showed an entry for a “Personal Computer mini-PC (NUC14LNS) Asus AMD Ryzen AI Max-395/W 8060S,

This chip cojoins existing AMD CPU and GPU architectures, along with a high speed memory interface, in an unprecedented way, compared to traditional X86 chip designs.

Since taking over the NUC line of mini PCs from Intel in 2023, Asus has continued to offer small desktops with Intel and AMD processor options. But so far the company has only used the NUC brand for models with Intel processors, while marketing AMD-powered systems as ExpertCenter systems.

AMD has revealed new gaming benchmarks for the Ryzen AI Max "Strix Halo" APU via Wccftech, implying the integrated Radeon 8060S GPU is more powerful than the Nvidia RTX 4070 discrete mobile GPU.