Osteogenesis imperfecta (OI), also known as brittle bone disease,makes your bones thin and brittle.WebMD explains the causes, symptoms, and treatment of this genetic disorder.

Osteogenesis imperfecta also has many types with varying levels of symptoms caused. It is important to know more about this condition so that parents can also take the right steps if their little ...

The special issue 'Osteogenesis Imperfecta from Bench to Bedside and from Cradle to Grave', published in the journal Calcified Tissue International, is a compilation of 14 invited reviews and ...

Osteogenesis imperfecta (OI) is primarily caused by mutations in the COL1A1 or COL1A2 genes, which leads to a reduction in type 1 collagen production and changes in bone metabolism.

In an exclusive interview with PEOPLE, Jay and Pamela — both born with osteogenesis imperfecta, or brittle bone disease — open up about keeping a positive mindset despite challenges. They are ...