Objective The objective was to investigate changes in cognitive functioning in subjects with early multiple sclerosis (MS) over 5 years. Methodological issues associated with longitudinal cognitive ...

The brain is in a constant state of dynamic change, for example switching between cognitive and behavioural tasks, and between wakefulness and sleep. The brains of people with epilepsy have additional ...

Given the profound impact of language impairment after stroke (aphasia), neuroplasticity research is garnering considerable attention as means for eventually improving aphasia treatments and how they ...

Background Cognitive and behavioural dysfunction may occur in people with motor neuron disease (MND), with some studies suggesting an association with the C9ORF72 repeat expansion. Their onset and ...

Correspondence to: Professor Kerry R Mills Department of Clinical Neurophysiology, King’s College Hospital, Denmark Hill, London SE5 9RS, UK; kerry.mills1kingsch.nhs.uk Electromyography (EMG), the ...

Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

OBJECTIVES To evaluate the influences of chronic alcohol consumption on brain volume among social drinkers, as it is well known that alcohol misusers have a high risk of brain shrinkage. METHODS ...

OBJECTIVE To test the feasibility and validity of the EQ-5D (a widely used generic (disease non-specific) quality of life (QoL) instrument which allows comparisons between different patient groups and ...

Correspondence to: Dr Amin Kassam University of Pittsburgh Medical Center, Center for Cranial Nerve Disorders, Suite B-400, 200 Lothrop Street, Pittsburgh, PA 15213, USA; kassamabupmc.edu Objective: ...

An 18 year old girl presented with acute visual loss. T2 weighted brain MRI showed areas of hyperintensities in the thalamic nuclei, internal capsule, lentiform nuclei, the subarachnoidal spaces, and ...

Background In neurodegenerative diseases, alongside genetic factors, the possible intervention of environmental factors in the pathogenesis is increasingly being considered. In particular, recent ...

D G Healy, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; danhealy{at}doctors.org.uk If you wish to reuse any or all of this article ...