These platelets then release a series of chemicals that trigger the coagulation cascade, a critical process in wound healing. This cascade transforms fibrinogen, a soluble protein, into fibrin ...

since clot-bound thrombin retains its enzymatic activity and can continue to stimulate the coagulation cascade. [12] Dr. Gulseth has been a paid consultant to Aventis Pharmaceuticals and is a ...

Antibiotic therapy can also be an initiator of DIC, as it may alter intestinal flora, which is a source of vitamin K, thereby altering the coagulation process. DIC may also be related to blood ...

Coagulant Therapeutics—a privately held biotech company of seasoned drug developers specializing in biologics and the coagulation cascade—is here to fill that void. Drawing on over 100 years ...