BMJ1d
AB0132 AFIMETORAN (BMS-986256), AN EQUIPOTENT TLR7/8 ANTAGONIST, DEMONSTRATES STEROID-SPARING EFFECTS IN A LUPUS MOUSE MODEL
2 Biocon Bristol Myers Squibb Research Center, Discovery Biology, Bangalore, India 3 Bristol Myers Squibb, Medicinal Chemistry, Lawrenceville, United States of America 4 Bristol Myers Squibb, ...
BMJ2d
THU0265 Identifying the links between iron deficiency and fatigue in adolescents and young adults with systemic lupus erythematosus
Background Between 80–90% of patients with systemic lupus erythematosus (SLE) report fatigue to be the single most troublesome and debilitating symptom of their illness. 1 Recent studies have found ...
BMJ2d
POS0471 CONTINUOUSLY LOW MUSCLE MASS CONTRIBUTES TO WORSE PHYSICAL FUNCTION IN RHEUMATOID ARTHRITIS PATIENTS: A 5-YEAR FOLLOW-UP STUDY
Background: Rheumatoid arthritis (RA) is characterized with joint damage and physical dysfunction, leading to reducing quality of life. The causes of physical dysfunction in RA are multifactorial, ...
BMJ2d
Joachim Robert Kalden: one of the founders of autoimmunity research and immunotherapy
Correspondence to Prof. Dr. Gerd R Burmester, Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany; gerd.burmester{at}charite.de Born in ...
BMJ4d
Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group
20 Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, The Netherlands Correspondence to Dr Robert G W Lambert, Department of Radiology and Diagnostic Imaging, University ...
BMJ7d
Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy cessation
Correspondence to Dr Laura C Cappelli, Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA; lcappel1{at}jhmi.edu Objective We sought to investigate the long-term outcomes of ...
BMJ7d
Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7
Objectives To investigate the role of mechanical stress in cartilage ageing and identify the mechanistic association during osteoarthritis (OA) progression. Conclusions FBXW7 is a key factor in the ...
BMJ7d
Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome
Correspondence to Dr Mariana J Kaplan, Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MA ...
BMJ7d
Global, regional and national burden of osteoarthritis 1990-2017: a systematic analysis of the Global Burden of Disease Study 2017
Objectives To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and ...
BMJ7d
Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications
Objective Autoantibodies against antigens carrying distinct post-translational modifications (PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of rheumatoid arthritis (RA). The ...
BMJ8d
2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus
Correspondence to Martin Aringer, Medicine III, University Medical Center and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden D-01307, Germany; martin.aringer{at}uniklinikum-dresden.de; Dr ...
BMJ8d
Adalimumab dose tapering in patients with rheumatoid arthritis who are in long-standing clinical remission: results of the phase IV PREDICTRA study
Objective To investigate the association between baseline disease activity and the occurrence of flares after adalimumab tapering or withdrawal in patients with rheumatoid arthritis (RA) in sustained ...