Objective The objective was to investigate changes in cognitive functioning in subjects with early multiple sclerosis (MS) over 5 years. Methodological issues associated with longitudinal cognitive ...

The brain is in a constant state of dynamic change, for example switching between cognitive and behavioural tasks, and between wakefulness and sleep. The brains of people with epilepsy have additional ...

Background Cognitive and behavioural dysfunction may occur in people with motor neuron disease (MND), with some studies suggesting an association with the C9ORF72 repeat expansion. Their onset and ...

Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

OBJECTIVE To test the feasibility and validity of the EQ-5D (a widely used generic (disease non-specific) quality of life (QoL) instrument which allows comparisons between different patient groups and ...

OBJECTIVES To evaluate the influences of chronic alcohol consumption on brain volume among social drinkers, as it is well known that alcohol misusers have a high risk of brain shrinkage. METHODS ...

Dr JL Iddon, Department of Academic Neurosurgery, Box 167, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 5RG, UK email jo.iddon{at}cenes.co.uk OBJECTIVES Eleven patients ...

Centre for PET, Austin Health, Melbourne and Colin L Masters, Department of Pathology, University of Melbourne, Australia Background: Neuropathological studies have reported varying amounts of amyloid ...

D G Healy, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; danhealy{at}doctors.org.uk If you wish to reuse any or all of this article ...

Given the profound impact of language impairment after stroke (aphasia), neuroplasticity research is garnering considerable attention as means for eventually improving aphasia treatments and how they ...

1 Division of Neurology, Department of Medicine, University of Massachusetts, USA 2 Department of Neurology, Penn State College of Medicine, USA 3 Department of Neurology, University of Florida ...

1 Center for Brain and Cognition, University of California, San Diego, La Jolla, California, USA 2 Department of Radiology, University of California, San Diego, La Jolla, California, USA ...