BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...
As the most upstream component of the renin-angiotensin-aldosterone system, angiotensinogen represents an attractive target ...
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Mitochondrial dysfunction is a key factor in the development of atherogenesis. METTL4 (methyltransferase-like protein 4) mediates N6- methyldeoxyadenosine (6mA) of mammalian mitochondrial DNA (mtDNA).
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View all available purchase options and get full access to this article. Wagner R, Heni M, Tabak AG, Machann J, Schick F, Randrianarisoa E, Hrabe de Angelis M, Birkenfeld AL, Stefan N, Peter A, et al.
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Cardiovascular diseases account for approximately 30% of deaths worldwide and remain a leading cause of morbidity and mortality globally, driving the need for ongoing major research investments. These ...