He had a history of atrial fibrillation (AF) that initially occurred 2 years before in the context of streptococcal ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...

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Mitochondrial dysfunction is a key factor in the development of atherogenesis. METTL4 (methyltransferase-like protein 4) mediates N6- methyldeoxyadenosine (6mA) of mammalian mitochondrial DNA (mtDNA).

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Our understanding of hypertension and the ability to lower blood pressure (BP) with pharmacotherapy advanced immensely during the second half of the 20th century and the early 21st century. However, ...

Myocardial infarction (MI) is a complex disease caused by both lifestyle and genetic factors. This study aims to investigate the predictive value of genetic risk, in addition to traditional ...

Department of Neurosurgery and Neurology (Y.X., B.S., C.L., C.W., J.D., R.M., F.Y., J.C., X.J.), Xuanwu Hospital, Capital Medical University. China-America Institute ...

Heart failure with preserved ejection fraction (HFpEF) is a major public health problem characterized by multiple simultaneous comorbidities whose specific contribution is challenging to disentangle ...

Declining cardiovascular mortality rates have been well-documented, yet temporal trends of sudden cardiac death (SCD) in young individuals remain unclear. We provide contemporary nationwide estimates ...

Cardiovascular Division and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville. For Sources of Funding and Disclosures, see page ...